BDBM50052595 3-(3,4-Diethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propionamide::CHEMBL322553

SMILES: CCOc1ccc(cc1OCC)C(CC(N)=O)N1C(=O)c2ccccc2C1=O

InChI Key: InChIKey=WTGUYKUCSLEJTB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052595   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tumor necrosis factor (Homo sapiens (Human))	BDBM50052595 (3-(3,4-Diethoxy-phenyl)-3-(1,3-dioxo-1,3-dihydro-i...) Show SMILES CCOc1ccc(cc1OCC)C(CC(N)=O)N1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C21H22N2O5/c1-3-27-17-10-9-13(11-18(17)28-4-2)16(12-19(22)24)23-20(25)14-7-5-6-8-15(14)21(23)26/h5-11,16H,3-4,12H2,1-2H3,(H2,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of TNF-alpha production in LPS stimulated human PBMCs				J Med Chem 39: 3238-40 (1996) Article DOI: 10.1021/jm9603328 BindingDB Entry DOI: 10.7270/Q2V40T9Q
					More data for this Ligand-Target Pair