BindingDB logo
myBDB logout

null

SMILES: O=C(N1CCN(CC1)c1ncccn1)c1ccc(cc1)-n1cccc1

InChI Key: InChIKey=GAKALYOZKAXZGM-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052651   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent proline transporter


(Homo sapiens (Human))		BDBM50052651
PNG
(CHEMBL3318560)
Show SMILES O=C(N1CCN(CC1)c1ncccn1)c1ccc(cc1)-n1cccc1
Show InChI InChI=1S/C19H19N5O/c25-18(16-4-6-17(7-5-16)22-10-1-2-11-22)23-12-14-24(15-13-23)19-20-8-3-9-21-19/h1-11H,12-15H2
UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
Article
PubMed
n/an/a 2.23E+3n/an/an/an/an/an/a



Lexicon Pharmaceuticals

Curated by ChEMBL


Assay Description
Inhibition of human high-affinity L-proline transporter expressed in COS1 cells by [3H]proline uptake assay

Bioorg Med Chem Lett 24: 3886-90 (2014)


Article DOI: 10.1016/j.bmcl.2014.06.049
BindingDB Entry DOI: 10.7270/Q20C4XDG
More data for this
Ligand-Target Pair