BDBM50052722 CHEMBL3318578

SMILES: CN(C)C(=O)C1CN(CCN1C(=O)c1ccc(cc1)-c1cccc(Cl)c1)c1ncccn1

InChI Key: InChIKey=RTTLZSSZKSRTED-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50052722   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent proline transporter (Homo sapiens (Human))	BDBM50052722 (CHEMBL3318578) Show SMILES CN(C)C(=O)C1CN(CCN1C(=O)c1ccc(cc1)-c1cccc(Cl)c1)c1ncccn1 Show InChI InChI=1S/C24H24ClN5O2/c1-28(2)23(32)21-16-29(24-26-11-4-12-27-24)13-14-30(21)22(31)18-9-7-17(8-10-18)19-5-3-6-20(25)15-19/h3-12,15,21H,13-14,16H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	392	n/a	n/a	n/a	n/a	n/a	n/a
Lexicon Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human high-affinity L-proline transporter expressed in COS1 cells by [3H]proline uptake assay				Bioorg Med Chem Lett 24: 3886-90 (2014) Article DOI: 10.1016/j.bmcl.2014.06.049 BindingDB Entry DOI: 10.7270/Q20C4XDG
					More data for this Ligand-Target Pair