BDBM50052859 (R)-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinolin-11-ol::CHEMBL116367

SMILES: Cc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O

InChI Key: InChIKey=MNRGHKYZSUNTQE-CQSZACIVSA-N

Data: 6 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50052859   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50052859 ((R)-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]...) Show SMILES Cc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O Show InChI InChI=1S/C17H17NO/c1-10-5-6-12-9-14-15-11(7-8-18-14)3-2-4-13(15)16(12)17(10)19/h2-6,14,18-19H,7-9H2,1H3/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro affinity at 5-hydroxytryptamine 1A receptor of rat hippocampus by [3H]-8-OH-DPAT displacement.				J Med Chem 39: 3491-502 (1996) Article DOI: 10.1021/jm960188q BindingDB Entry DOI: 10.7270/Q2XW4HXS
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50052859 ((R)-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]...) Show SMILES Cc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O Show InChI InChI=1S/C17H17NO/c1-10-5-6-12-9-14-15-11(7-8-18-14)3-2-4-13(15)16(12)17(10)19/h2-6,14,18-19H,7-9H2,1H3/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from rat 5HT1A receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50052859 ((R)-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]...) Show SMILES Cc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O Show InChI InChI=1S/C17H17NO/c1-10-5-6-12-9-14-15-11(7-8-18-14)3-2-4-13(15)16(12)17(10)19/h2-6,14,18-19H,7-9H2,1H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]raclopride from rat dopamine D2 receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50052859 ((R)-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]...) Show SMILES Cc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O Show InChI InChI=1S/C17H17NO/c1-10-5-6-12-9-14-15-11(7-8-18-14)3-2-4-13(15)16(12)17(10)19/h2-6,14,18-19H,7-9H2,1H3/t14-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro affinity at human cloned Dopamine receptor D2A by [3H]-raclopride displacement.				J Med Chem 39: 3491-502 (1996) Article DOI: 10.1021/jm960188q BindingDB Entry DOI: 10.7270/Q2XW4HXS
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50052859 ((R)-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]...) Show SMILES Cc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O Show InChI InChI=1S/C17H17NO/c1-10-5-6-12-9-14-15-11(7-8-18-14)3-2-4-13(15)16(12)17(10)19/h2-6,14,18-19H,7-9H2,1H3/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Displacement of [3H]SCH-23390 from rat dopamine D1 receptor				J Med Chem 50: 171-81 (2007) Article DOI: 10.1021/jm060959i BindingDB Entry DOI: 10.7270/Q22J6CPJ
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50052859 ((R)-10-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]...) Show SMILES Cc1ccc2C[C@H]3NCCc4cccc(c34)-c2c1O Show InChI InChI=1S/C17H17NO/c1-10-5-6-12-9-14-15-11(7-8-18-14)3-2-4-13(15)16(12)17(10)19/h2-6,14,18-19H,7-9H2,1H3/t14-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.38E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description In vitro affinity at Dopamine receptor D1 of rat striatum by [3H]-SCH-23,390 displacement.				J Med Chem 39: 3491-502 (1996) Article DOI: 10.1021/jm960188q BindingDB Entry DOI: 10.7270/Q2XW4HXS
					More data for this Ligand-Target Pair