BDBM50053032 CHEMBL3318741

SMILES: Oc1ccc(\C=N\NC(=O)c2cccc(c2)C(=O)N\N=C\c2ccc(O)cc2O)c(O)c1

InChI Key: InChIKey=IPLAOLSAINWMRJ-ASIDMNOUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053032   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly(ADP-ribose) glycohydrolase (Rattus norvegicus)	BDBM50053032 (CHEMBL3318741) Show SMILES Oc1ccc(\C=N\NC(=O)c2cccc(c2)C(=O)N\N=C\c2ccc(O)cc2O)c(O)c1 Show InChI InChI=1S/C22H18N4O6/c27-17-6-4-15(19(29)9-17)11-23-25-21(31)13-2-1-3-14(8-13)22(32)26-24-12-16-5-7-18(28)10-20(16)30/h1-12,27-30H,(H,25,31)(H,26,32)/b23-11+,24-12+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kumamoto Health Science University Curated by ChEMBL					Assay Description Inhibition of rat testis GST-tagged PARG catalytic activity after 30 mins using [32P]poly(ADP-ribose) by radioassay				Bioorg Med Chem Lett 24: 3802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.065 BindingDB Entry DOI: 10.7270/Q2348N18
					More data for this Ligand-Target Pair