null

SMILES: Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCOCCOCCOCCOCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1

InChI Key: InChIKey=VCSXUTPJFQYQHZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50053417   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50053417 (CHEMBL3318851) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCOCCOCCOCCOCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1 Show InChI InChI=1S/C62H74Cl2F2N8O10/c63-51-13-9-49(10-14-51)61(25-31-71(32-26-61)29-1-3-57(75)47-5-17-53(65)18-6-47)83-59(77)23-21-55-45-73(69-67-55)35-37-79-39-41-81-43-44-82-42-40-80-38-36-74-46-56(68-70-74)22-24-60(78)84-62(50-11-15-52(64)16-12-50)27-33-72(34-28-62)30-2-4-58(76)48-7-19-54(66)20-8-48/h5-20,45-46H,1-4,21-44H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D2long receptor stably expressed in CHO cell membranes by competitive binding assay				Bioorg Med Chem Lett 24: 3753-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.079 BindingDB Entry DOI: 10.7270/Q2FF3V0M
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50053417 (CHEMBL3318851) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCOCCOCCOCCOCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1 Show InChI InChI=1S/C62H74Cl2F2N8O10/c63-51-13-9-49(10-14-51)61(25-31-71(32-26-61)29-1-3-57(75)47-5-17-53(65)18-6-47)83-59(77)23-21-55-45-73(69-67-55)35-37-79-39-41-81-43-44-82-42-40-80-38-36-74-46-56(68-70-74)22-24-60(78)84-62(50-11-15-52(64)16-12-50)27-33-72(34-28-62)30-2-4-58(76)48-7-19-54(66)20-8-48/h5-20,45-46H,1-4,21-44H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D2short receptor stably expressed in CHO cell membranes by competitive binding assay				Bioorg Med Chem Lett 24: 3753-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.079 BindingDB Entry DOI: 10.7270/Q2FF3V0M
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50053417 (CHEMBL3318851) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCOCCOCCOCCOCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1 Show InChI InChI=1S/C62H74Cl2F2N8O10/c63-51-13-9-49(10-14-51)61(25-31-71(32-26-61)29-1-3-57(75)47-5-17-53(65)18-6-47)83-59(77)23-21-55-45-73(69-67-55)35-37-79-39-41-81-43-44-82-42-40-80-38-36-74-46-56(68-70-74)22-24-60(78)84-62(50-11-15-52(64)16-12-50)27-33-72(34-28-62)30-2-4-58(76)48-7-19-54(66)20-8-48/h5-20,45-46H,1-4,21-44H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D3 receptor stably expressed in CHO cell membranes by competitive binding assay				Bioorg Med Chem Lett 24: 3753-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.079 BindingDB Entry DOI: 10.7270/Q2FF3V0M
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50053417 (CHEMBL3318851) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCOCCOCCOCCOCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1 Show InChI InChI=1S/C62H74Cl2F2N8O10/c63-51-13-9-49(10-14-51)61(25-31-71(32-26-61)29-1-3-57(75)47-5-17-53(65)18-6-47)83-59(77)23-21-55-45-73(69-67-55)35-37-79-39-41-81-43-44-82-42-40-80-38-36-74-46-56(68-70-74)22-24-60(78)84-62(50-11-15-52(64)16-12-50)27-33-72(34-28-62)30-2-4-58(76)48-7-19-54(66)20-8-48/h5-20,45-46H,1-4,21-44H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D4.4 receptor stably expressed in CHO cell membranes by competitive binding assay				Bioorg Med Chem Lett 24: 3753-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.079 BindingDB Entry DOI: 10.7270/Q2FF3V0M
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Sus scrofa)	BDBM50053417 (CHEMBL3318851) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC(CC1)(OC(=O)CCc1cn(CCOCCOCCOCCOCCn2cc(CCC(=O)OC3(CCN(CCCC(=O)c4ccc(F)cc4)CC3)c3ccc(Cl)cc3)nn2)nn1)c1ccc(Cl)cc1 Show InChI InChI=1S/C62H74Cl2F2N8O10/c63-51-13-9-49(10-14-51)61(25-31-71(32-26-61)29-1-3-57(75)47-5-17-53(65)18-6-47)83-59(77)23-21-55-45-73(69-67-55)35-37-79-39-41-81-43-44-82-42-40-80-38-36-74-46-56(68-70-74)22-24-60(78)84-62(50-11-15-52(64)16-12-50)27-33-72(34-28-62)30-2-4-58(76)48-7-19-54(66)20-8-48/h5-20,45-46H,1-4,21-44H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from porcine striatal membranes D1 receptor by competitive binding assay				Bioorg Med Chem Lett 24: 3753-6 (2014) Article DOI: 10.1016/j.bmcl.2014.06.079 BindingDB Entry DOI: 10.7270/Q2FF3V0M
					More data for this Ligand-Target Pair