BDBM50053522 1-{7-[3-(4-Hydroxy-tetrahydro-pyran-4-yl)-benzyloxy]-4-phenyl-naphthalen-2-yl}-ethanone::CHEMBL128821

SMILES: CC(=O)c1cc(-c2ccccc2)c2ccc(OCc3cccc(c3)C3(O)CCOCC3)cc2c1

InChI Key: InChIKey=CTSJGJBJQLBSTN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50053522 (1-{7-[3-(4-Hydroxy-tetrahydro-pyran-4-yl)-benzylox...) Show SMILES CC(=O)c1cc(-c2ccccc2)c2ccc(OCc3cccc(c3)C3(O)CCOCC3)cc2c1 Show InChI InChI=1S/C30H28O4/c1-21(31)24-17-25-18-27(10-11-28(25)29(19-24)23-7-3-2-4-8-23)34-20-22-6-5-9-26(16-22)30(32)12-14-33-15-13-30/h2-11,16-19,32H,12-15,20H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenase				J Med Chem 39: 3951-70 (1996) Article DOI: 10.1021/jm960301c BindingDB Entry DOI: 10.7270/Q2639QCJ
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