BDBM50053566 4-{3-[7-(4,5-Dihydro-thiazol-2-yl)-5-furan-3-yl-naphthalen-2-yloxymethyl]-phenyl}-tetrahydro-pyran-4-ol::CHEMBL128300

SMILES: OC1(CCOCC1)c1cccc(COc2ccc3c(cc(cc3c2)C2=NCCS2)-c2ccoc2)c1

InChI Key: InChIKey=AFWQLFMODNHFNK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50053566   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Homo sapiens (Human))	BDBM50053566 (4-{3-[7-(4,5-Dihydro-thiazol-2-yl)-5-furan-3-yl-na...) Show SMILES OC1(CCOCC1)c1cccc(COc2ccc3c(cc(cc3c2)C2=NCCS2)-c2ccoc2)c1 |t:27| Show InChI InChI=1S/C29H27NO4S/c31-29(7-11-32-12-8-29)24-3-1-2-20(14-24)18-34-25-4-5-26-22(16-25)15-23(28-30-9-13-35-28)17-27(26)21-6-10-33-19-21/h1-6,10,14-17,19,31H,7-9,11-13,18H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenase				J Med Chem 39: 3951-70 (1996) Article DOI: 10.1021/jm960301c BindingDB Entry DOI: 10.7270/Q2639QCJ
					More data for this Ligand-Target Pair