BDBM50053895 Allyl-(9-allyl-2-{4-[(2,3,4-trimethoxy-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylmethyl)-amino]-piperidin-1-yl}-9H-purin-6-yl)-amine::CHEMBL336560
SMILES: COc1cc2CCc3ccccc3C(CNC3CCN(CC3)c3nc(NCC=C)c4ncn(CC=C)c4n3)c2c(OC)c1OC
InChI Key: InChIKey=GLGUOWFHHASVGA-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Voltage-gated L-type calcium channel (Rattus norvegicus) | BDBM50053895 (Allyl-(9-allyl-2-{4-[(2,3,4-trimethoxy-10,11-dihyd...) | PDB MMDB B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut de Recherches Servier Curated by ChEMBL | Assay Description Inhibition of [3H]-D-888 binding to L-type [Ca2+] channel of membranes from rat skeletal muscle | J Med Chem 39: 4099-108 (1996) Article DOI: 10.1021/jm960361i BindingDB Entry DOI: 10.7270/Q2Q81C52 | |||||||||||
More data for this Ligand-Target Pair |