BDBM50054117 1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl)piperidine::1-[3-(5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-propyl]-piperidine::CHEMBL134607

SMILES: COc1cccc2C(CCCN3CCCCC3)CCCc12

InChI Key: InChIKey=OECXRJKGMSAVLR-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50054117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sigma non-opioid intracellular receptor 1 (Cavia porcellus (Guinea pig))	BDBM50054117 (1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1cccc2C(CCCN3CCCCC3)CCCc12 Show InChI InChI=1S/C19H29NO/c1-21-19-12-6-10-17-16(8-5-11-18(17)19)9-7-15-20-13-3-2-4-14-20/h6,10,12,16H,2-5,7-9,11,13-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H](+)-pentazocine ((+)-[2S-(2R,6R,11R)]-1,2,3,4,5,6-hexahydro-6,11-dimethyl- 3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocine- 8-ol...				J Med Chem 52: 7817-28 (2009) Article DOI: 10.1021/jm9007505 BindingDB Entry DOI: 10.7270/Q2CJ8FDB
					More data for this Ligand-Target Pair
3-beta-hydroxysteroid-delta(8),delta(7)-isomerase (Cavia porcellus)	BDBM50054117 (1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1cccc2C(CCCN3CCCCC3)CCCc12 Show InChI InChI=1S/C19H29NO/c1-21-19-12-6-10-17-16(8-5-11-18(17)19)9-7-15-20-13-3-2-4-14-20/h6,10,12,16H,2-5,7-9,11,13-15H2,1H3	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H](+/-)-emopamil from EBP in Dunkin guinea pig liver membrane by radioreceptor binding assay				J Med Chem 52: 7817-28 (2009) Article DOI: 10.1021/jm9007505 BindingDB Entry DOI: 10.7270/Q2CJ8FDB
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50054117 (1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1cccc2C(CCCN3CCCCC3)CCCc12 Show InChI InChI=1S/C19H29NO/c1-21-19-12-6-10-17-16(8-5-11-18(17)19)9-7-15-20-13-3-2-4-14-20/h6,10,12,16H,2-5,7-9,11,13-15H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Bari Curated by ChEMBL					Assay Description Displacement of [3H](+/-)-pentazocine from sigma 1 receptor in rat whole brain				J Med Chem 52: 7817-28 (2009) Article DOI: 10.1021/jm9007505 BindingDB Entry DOI: 10.7270/Q2CJ8FDB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054117 (1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1cccc2C(CCCN3CCCCC3)CCCc12 Show InChI InChI=1S/C19H29NO/c1-21-19-12-6-10-17-16(8-5-11-18(17)19)9-7-15-20-13-3-2-4-14-20/h6,10,12,16H,2-5,7-9,11,13-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on 5-hydroxytryptamine 1A receptor using radioligand [3H]5-HT binding assay.				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50054117 (1-(3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)...) Show SMILES COc1cccc2C(CCCN3CCCCC3)CCCc12 Show InChI InChI=1S/C19H29NO/c1-21-19-12-6-10-17-16(8-5-11-18(17)19)9-7-15-20-13-3-2-4-14-20/h6,10,12,16H,2-5,7-9,11,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Bari Curated by ChEMBL					Assay Description Binding affinity was tested on Dopamine receptor D2 using radioligand [3H]spiroperidol				J Med Chem 39: 4255-60 (1996) Article DOI: 10.1021/jm9508898 BindingDB Entry DOI: 10.7270/Q2RX9CRK
					More data for this Ligand-Target Pair