BDBM50054145 5-methoxy-1'-propylspiro[3,4-dihydro-2H-chromene-3,2'-(tetrahydro-1'H-pyrrole)]::CHEMBL422453

SMILES: CCCN1CCCC11COc2cccc(OC)c2C1

InChI Key: InChIKey=VNEQQDVYANFDGN-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054145   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054145 (5-methoxy-1'-propylspiro[3,4-dihydro-2H-chromene-3...) Show SMILES CCCN1CCCC11COc2cccc(OC)c2C1 Show InChI InChI=1S/C16H23NO2/c1-3-9-17-10-5-8-16(17)11-13-14(18-2)6-4-7-15(13)19-12-16/h4,6-7H,3,5,8-12H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	74.6	n/a	n/a	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description Binding affinity to 5-hydroxytryptamine 1A receptor in rat hippocampus membranes,3H-8-OH-DPAT and buspirone for nonspecific binding (NSB)				J Med Chem 39: 4285-98 (1996) Article DOI: 10.1021/jm950861w BindingDB Entry DOI: 10.7270/Q2XP741N
					More data for this Ligand-Target Pair
DRD1 (BOVINE)	BDBM50054145 (5-methoxy-1'-propylspiro[3,4-dihydro-2H-chromene-3...) Show SMILES CCCN1CCCC11COc2cccc(OC)c2C1 Show InChI InChI=1S/C16H23NO2/c1-3-9-17-10-5-8-16(17)11-13-14(18-2)6-4-7-15(13)19-12-16/h4,6-7H,3,5,8-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from Dopamine receptor D1 of calf striatum				J Med Chem 39: 4285-98 (1996) Article DOI: 10.1021/jm950861w BindingDB Entry DOI: 10.7270/Q2XP741N
					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50054145 (5-methoxy-1'-propylspiro[3,4-dihydro-2H-chromene-3...) Show SMILES CCCN1CCCC11COc2cccc(OC)c2C1 Show InChI InChI=1S/C16H23NO2/c1-3-9-17-10-5-8-16(17)11-13-14(18-2)6-4-7-15(13)19-12-16/h4,6-7H,3,5,8-12H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description Displacement of [3H]-SDZ-205-501 from Dopamine receptor D2 in calf caudate nucleus.				J Med Chem 39: 4285-98 (1996) Article DOI: 10.1021/jm950861w BindingDB Entry DOI: 10.7270/Q2XP741N
					More data for this Ligand-Target Pair
Serotonin 1B/1D receptor (Rattus norvegicus (Rat))	BDBM50054145 (5-methoxy-1'-propylspiro[3,4-dihydro-2H-chromene-3...) Show SMILES CCCN1CCCC11COc2cccc(OC)c2C1 Show InChI InChI=1S/C16H23NO2/c1-3-9-17-10-5-8-16(17)11-13-14(18-2)6-4-7-15(13)19-12-16/h4,6-7H,3,5,8-12H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Université d'Orléans Curated by ChEMBL					Assay Description Binding affinity to 5-HT1B receptors using rat cortex+striatum + globus pallidus,[3H]-5-OH-tryptamine, and serotonin for NSB				J Med Chem 39: 4285-98 (1996) Article DOI: 10.1021/jm950861w BindingDB Entry DOI: 10.7270/Q2XP741N
					More data for this Ligand-Target Pair