BDBM50054377 2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-tetrahydro-pyrrolo[1,2-c]imidazole-1,3-dione::CHEMBL42881

SMILES: Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccc(F)cc1

InChI Key: InChIKey=QPMIMXRKACZEBE-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50054377   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054377 (2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-tetra...) Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C17H21FN4O2/c18-13-3-5-14(6-4-13)20-10-8-19(9-11-20)12-22-16(23)15-2-1-7-21(15)17(22)24/h3-6,23H,1-2,7-12H2	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards rat 5-hydroxytryptamine 1A receptor using [3H]-8-OH-DPAT radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50054377 (2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-tetra...) Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C17H21FN4O2/c18-13-3-5-14(6-4-13)20-10-8-19(9-11-20)12-22-16(23)15-2-1-7-21(15)17(22)24/h3-6,23H,1-2,7-12H2	PDB KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description In vitro binding affinity against 5-hydroxytryptamine 1A receptor of rat cerebral cortex using [3H]8-OH-DPAT as radioligand.				J Med Chem 40: 1648-56 (1997) Article DOI: 10.1021/jm960744g BindingDB Entry DOI: 10.7270/Q2K35V96
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50054377 (2-[4-(4-Fluoro-phenyl)-piperazin-1-ylmethyl]-tetra...) Show SMILES Oc1c2CCCn2c(=O)n1CN1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C17H21FN4O2/c18-13-3-5-14(6-4-13)20-10-8-19(9-11-20)12-22-16(23)15-2-1-7-21(15)17(22)24/h3-6,23H,1-2,7-12H2	PDB Reactome pathway KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad Complutense Curated by ChEMBL					Assay Description Binding affinity towards dopamine receptor D2 using [3H]-raclopride radioligand.				J Med Chem 39: 4439-50 (1996) Article DOI: 10.1021/jm960416g BindingDB Entry DOI: 10.7270/Q2WS8SBN
					More data for this Ligand-Target Pair