BDBM50054732 (2S,5R)-2,5-Dimethyl-1-(3-phenyl-propyl)-piperazine::CHEMBL143407

SMILES: C[C@@H]1CN(CCCc2ccccc2)[C@@H](C)CN1

InChI Key: InChIKey=GFDDXUQTWACMNH-KGLIPLIRSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50054732   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50054732 ((2S,5R)-2,5-Dimethyl-1-(3-phenyl-propyl)-piperazin...) Show SMILES C[C@@H]1CN(CCCc2ccccc2)[C@@H](C)CN1 Show InChI InChI=1S/C15H24N2/c1-13-12-17(14(2)11-16-13)10-6-9-15-7-4-3-5-8-15/h3-5,7-8,13-14,16H,6,9-12H2,1-2H3/t13-,14+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of dopamine DA reuptake				J Med Chem 39: 4704-16 (1997) Article DOI: 10.1021/jm960305h BindingDB Entry DOI: 10.7270/Q2QZ2BN6
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50054732 ((2S,5R)-2,5-Dimethyl-1-(3-phenyl-propyl)-piperazin...) Show SMILES C[C@@H]1CN(CCCc2ccccc2)[C@@H](C)CN1 Show InChI InChI=1S/C15H24N2/c1-13-12-17(14(2)11-16-13)10-6-9-15-7-4-3-5-8-15/h3-5,7-8,13-14,16H,6,9-12H2,1-2H3/t13-,14+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding affinity against sigma receptor using radioligand ([3H](+)-pentazocine) binding assay				J Med Chem 39: 4704-16 (1997) Article DOI: 10.1021/jm960305h BindingDB Entry DOI: 10.7270/Q2QZ2BN6
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50054732 ((2S,5R)-2,5-Dimethyl-1-(3-phenyl-propyl)-piperazin...) Show SMILES C[C@@H]1CN(CCCc2ccccc2)[C@@H](C)CN1 Show InChI InChI=1S/C15H24N2/c1-13-12-17(14(2)11-16-13)10-6-9-15-7-4-3-5-8-15/h3-5,7-8,13-14,16H,6,9-12H2,1-2H3/t13-,14+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Inhibition of [3H]5-HT reuptake at rat serotonin transporter				J Med Chem 39: 4704-16 (1997) Article DOI: 10.1021/jm960305h BindingDB Entry DOI: 10.7270/Q2QZ2BN6
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50054732 ((2S,5R)-2,5-Dimethyl-1-(3-phenyl-propyl)-piperazin...) Show SMILES C[C@@H]1CN(CCCc2ccccc2)[C@@H](C)CN1 Show InChI InChI=1S/C15H24N2/c1-13-12-17(14(2)11-16-13)10-6-9-15-7-4-3-5-8-15/h3-5,7-8,13-14,16H,6,9-12H2,1-2H3/t13-,14+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Binding against Dopamine transporter using radioligand as [3H]GBR 12935				J Med Chem 39: 4704-16 (1997) Article DOI: 10.1021/jm960305h BindingDB Entry DOI: 10.7270/Q2QZ2BN6
					More data for this Ligand-Target Pair