BDBM50055124 CHEMBL148739::N-Hydroxy-N-[2,3-dihydro-7-(benzyloxy)benzofuran-3-yl]urea

SMILES: NC(=O)N(O)C1COc2ccc(Oc3ccccc3)cc12

InChI Key: InChIKey=ZNQGRDJOUUDKBL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055124   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50055124 (CHEMBL148739 | N-Hydroxy-N-[2,3-dihydro-7-(benzylo...) Show SMILES NC(=O)N(O)C1COc2ccc(Oc3ccccc3)cc12 Show InChI InChI=1S/C15H14N2O4/c16-15(18)17(19)13-9-20-14-7-6-11(8-12(13)14)21-10-4-2-1-3-5-10/h1-8,13,19H,9H2,(H2,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.				J Med Chem 39: 5035-46 (1997) Article DOI: 10.1021/jm960271d BindingDB Entry DOI: 10.7270/Q2Q23ZB1
					More data for this Ligand-Target Pair