BDBM50055129 CHEMBL148845::N-Hydroxy-N-[1,2,3,4-tetrahydro-6-(phenyl)-1-naphthalenyl]urea

SMILES: NC(=O)N(O)C1CCCc2cc(ccc12)-c1ccccc1

InChI Key: InChIKey=MIKGWGZEJCXYMY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50055129 (CHEMBL148845 | N-Hydroxy-N-[1,2,3,4-tetrahydro-6-(...) Show SMILES NC(=O)N(O)C1CCCc2cc(ccc12)-c1ccccc1 Show InChI InChI=1S/C17H18N2O2/c18-17(20)19(21)16-8-4-7-14-11-13(9-10-15(14)16)12-5-2-1-3-6-12/h1-3,5-6,9-11,16,21H,4,7-8H2,(H2,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.				J Med Chem 39: 5035-46 (1997) Article DOI: 10.1021/jm960271d BindingDB Entry DOI: 10.7270/Q2Q23ZB1
					More data for this Ligand-Target Pair