BDBM50055136 CHEMBL358414::N-Hydroxy-N-[1,2,3,4-tetrahydro-5-(benzyloxy)-1-naphthalenyl]urea

SMILES: NC(=O)N(O)C1CCCc2c(OCc3ccccc3)cccc12

InChI Key: InChIKey=BDHUOQDXDBBOCW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055136   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50055136 (CHEMBL358414 | N-Hydroxy-N-[1,2,3,4-tetrahydro-5-(...) Show SMILES NC(=O)N(O)C1CCCc2c(OCc3ccccc3)cccc12 Show InChI InChI=1S/C18H20N2O3/c19-18(21)20(22)16-10-4-9-15-14(16)8-5-11-17(15)23-12-13-6-2-1-3-7-13/h1-3,5-8,11,16,22H,4,9-10,12H2,(H2,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	910	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.				J Med Chem 39: 5035-46 (1997) Article DOI: 10.1021/jm960271d BindingDB Entry DOI: 10.7270/Q2Q23ZB1
					More data for this Ligand-Target Pair