BDBM50055140 CHEMBL424122::bicyclic N-hydroxy urea derivatives

SMILES: NC(=O)N(O)C1COc2c1ccc1ccccc21

InChI Key: InChIKey=RZIXULQOGAETTQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055140   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50055140 (CHEMBL424122 | bicyclic N-hydroxy urea derivatives) Show SMILES NC(=O)N(O)C1COc2c1ccc1ccccc21 Show InChI InChI=1S/C13H12N2O3/c14-13(16)15(17)11-7-18-12-9-4-2-1-3-8(9)5-6-10(11)12/h1-6,11,17H,7H2,(H2,14,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.				J Med Chem 39: 5035-46 (1997) Article DOI: 10.1021/jm960271d BindingDB Entry DOI: 10.7270/Q2Q23ZB1
					More data for this Ligand-Target Pair