BDBM50055143 CHEMBL149384::bicyclic N-hydroxy urea derivatives

SMILES: NC(=O)N(O)C1CCn2c1cc1cc(OCc3ccccc3)ccc21

InChI Key: InChIKey=OLQZOGIEDMKSOH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055143   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arachidonate 5-lipoxygenase (Rattus norvegicus)	BDBM50055143 (CHEMBL149384 | bicyclic N-hydroxy urea derivatives) Show SMILES NC(=O)N(O)C1CCn2c1cc1cc(OCc3ccccc3)ccc21 Show InChI InChI=1S/C19H19N3O3/c20-19(23)22(24)17-8-9-21-16-7-6-15(10-14(16)11-18(17)21)25-12-13-4-2-1-3-5-13/h1-7,10-11,17,24H,8-9,12H2,(H2,20,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Inhibitory activity against rat 5-lipoxygenase by using continuous oxygen consumption assay.				J Med Chem 39: 5035-46 (1997) Article DOI: 10.1021/jm960271d BindingDB Entry DOI: 10.7270/Q2Q23ZB1
					More data for this Ligand-Target Pair