BDBM50055280 2-(2-Fluoro-ethyl)-isothiourea::CHEMBL148951

SMILES: NC(=N)SCCF

InChI Key: InChIKey=OOOBJDSBUDMEPW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50055280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, endothelial (Homo sapiens (Human))	BDBM50055280 (2-(2-Fluoro-ethyl)-isothiourea | CHEMBL148951) Show SMILES NC(=N)SCCF Show InChI InChI=1S/C3H7FN2S/c4-1-2-7-3(5)6/h1-2H2,(H3,5,6)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Medical School Curated by ChEMBL					Assay Description The compound was evaluated for the inhibitory potencies using human Endothelial nitric oxide synthase				J Med Chem 39: 5110-8 (1997) Article DOI: 10.1021/jm960481q BindingDB Entry DOI: 10.7270/Q29W0DKZ
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Homo sapiens (Human))	BDBM50055280 (2-(2-Fluoro-ethyl)-isothiourea | CHEMBL148951) Show SMILES NC(=N)SCCF Show InChI InChI=1S/C3H7FN2S/c4-1-2-7-3(5)6/h1-2H2,(H3,5,6)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Washington University Medical School Curated by ChEMBL					Assay Description The compound was evaluated for the inhibitory potencies using human Inducible nitric oxide synthase (hiNOS)				J Med Chem 39: 5110-8 (1997) Article DOI: 10.1021/jm960481q BindingDB Entry DOI: 10.7270/Q29W0DKZ
					More data for this Ligand-Target Pair