BDBM50055332 4-(1-Benzyl-3-carbamoylmethyl-1H-indol-5-yloxy)-butyric acid::CHEMBL148813

SMILES: NC(=O)Cc1cn(Cc2ccccc2)c2ccc(OCCCC(O)=O)cc12

InChI Key: InChIKey=KNJYWLTULWCZIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50055332 (4-(1-Benzyl-3-carbamoylmethyl-1H-indol-5-yloxy)-bu...) Show SMILES NC(=O)Cc1cn(Cc2ccccc2)c2ccc(OCCCC(O)=O)cc12 Show InChI InChI=1S/C21H22N2O4/c22-20(24)11-16-14-23(13-15-5-2-1-3-6-15)19-9-8-17(12-18(16)19)27-10-4-7-21(25)26/h1-3,5-6,8-9,12,14H,4,7,10-11,13H2,(H2,22,24)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay				J Med Chem 39: 5137-58 (1997) Article DOI: 10.1021/jm960486n BindingDB Entry DOI: 10.7270/Q2639NV0
					More data for this Ligand-Target Pair