BDBM50055365 CHEMBL149075::[3-(1-Benzyl-3-carbamoylmethyl-2-ethyl-6-isopropyl-1H-indol-5-yloxy)-propyl]-phosphonic acid

SMILES: CCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)c(cc2n1Cc1ccccc1)C(C)C

InChI Key: InChIKey=LBUQQWMQJWZCFC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055365   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2, membrane associated (Homo sapiens (Human))	BDBM50055365 (CHEMBL149075 | [3-(1-Benzyl-3-carbamoylmethyl-2-et...) Show SMILES CCc1c(CC(N)=O)c2cc(OCCCP(O)(O)=O)c(cc2n1Cc1ccccc1)C(C)C Show InChI InChI=1S/C25H33N2O5P/c1-4-22-21(15-25(26)28)20-14-24(32-11-8-12-33(29,30)31)19(17(2)3)13-23(20)27(22)16-18-9-6-5-7-10-18/h5-7,9-10,13-14,17H,4,8,11-12,15-16H2,1-3H3,(H2,26,28)(H2,29,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human non-pancreatic secretory phospholipase A2 (PLA2) in a chromogenic assay				J Med Chem 39: 5137-58 (1997) Article DOI: 10.1021/jm960486n BindingDB Entry DOI: 10.7270/Q2639NV0
					More data for this Ligand-Target Pair