BDBM50055666 4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (2R,3R)-3-(4-hydroxy-benzoylamino)-bicyclo[2.2.1]hept-2-yl ester::CHEMBL80525

SMILES: OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1C2CCC(C2)[C@H]1NC(=O)c1ccc(O)cc1

InChI Key: InChIKey=GQCWIZZVARXZGR-YPBHZARMSA-N

Data: 9 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50055666   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50055666 (4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1C2CCC(C2)[C@H]1NC(=O)c1ccc(O)cc1 |TLB:22:23:28:26.25,THB:30:29:28:26.25| Show InChI InChI=1S/C29H25NO10/c31-17-8-6-13(7-9-17)27(36)30-24-14-4-5-15(10-14)26(24)40-29(39)16-11-20(33)23(21(34)12-16)25(35)22-18(28(37)38)2-1-3-19(22)32/h1-3,6-9,11-12,14-15,24,26,31-34H,4-5,10H2,(H,30,36)(H,37,38)/t14?,15?,24-,26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
A Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human Protein kinase C alpha isozyme				J Med Chem 40: 226-35 (1997) Article DOI: 10.1021/jm960497g BindingDB Entry DOI: 10.7270/Q2J965HR
					More data for this Ligand-Target Pair
Protein kinase C, eta (Homo sapiens (Human))	BDBM50055666 (4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1C2CCC(C2)[C@H]1NC(=O)c1ccc(O)cc1 |TLB:22:23:28:26.25,THB:30:29:28:26.25| Show InChI InChI=1S/C29H25NO10/c31-17-8-6-13(7-9-17)27(36)30-24-14-4-5-15(10-14)26(24)40-29(39)16-11-20(33)23(21(34)12-16)25(35)22-18(28(37)38)2-1-3-19(22)32/h1-3,6-9,11-12,14-15,24,26,31-34H,4-5,10H2,(H,30,36)(H,37,38)/t14?,15?,24-,26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
A Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human Protein kinase C eta isozyme				J Med Chem 40: 226-35 (1997) Article DOI: 10.1021/jm960497g BindingDB Entry DOI: 10.7270/Q2J965HR
					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50055666 (4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1C2CCC(C2)[C@H]1NC(=O)c1ccc(O)cc1 |TLB:22:23:28:26.25,THB:30:29:28:26.25| Show InChI InChI=1S/C29H25NO10/c31-17-8-6-13(7-9-17)27(36)30-24-14-4-5-15(10-14)26(24)40-29(39)16-11-20(33)23(21(34)12-16)25(35)22-18(28(37)38)2-1-3-19(22)32/h1-3,6-9,11-12,14-15,24,26,31-34H,4-5,10H2,(H,30,36)(H,37,38)/t14?,15?,24-,26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
A Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human Protein kinase C beta 1 isozyme				J Med Chem 40: 226-35 (1997) Article DOI: 10.1021/jm960497g BindingDB Entry DOI: 10.7270/Q2J965HR
					More data for this Ligand-Target Pair
Protein kinase C, epsilon (Homo sapiens (Human))	BDBM50055666 (4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1C2CCC(C2)[C@H]1NC(=O)c1ccc(O)cc1 |TLB:22:23:28:26.25,THB:30:29:28:26.25| Show InChI InChI=1S/C29H25NO10/c31-17-8-6-13(7-9-17)27(36)30-24-14-4-5-15(10-14)26(24)40-29(39)16-11-20(33)23(21(34)12-16)25(35)22-18(28(37)38)2-1-3-19(22)32/h1-3,6-9,11-12,14-15,24,26,31-34H,4-5,10H2,(H,30,36)(H,37,38)/t14?,15?,24-,26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
A Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human Protein kinase C epsilon isozyme				J Med Chem 40: 226-35 (1997) Article DOI: 10.1021/jm960497g BindingDB Entry DOI: 10.7270/Q2J965HR
					More data for this Ligand-Target Pair
Protein kinase C, gamma (Homo sapiens (Human))	BDBM50055666 (4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1C2CCC(C2)[C@H]1NC(=O)c1ccc(O)cc1 |TLB:22:23:28:26.25,THB:30:29:28:26.25| Show InChI InChI=1S/C29H25NO10/c31-17-8-6-13(7-9-17)27(36)30-24-14-4-5-15(10-14)26(24)40-29(39)16-11-20(33)23(21(34)12-16)25(35)22-18(28(37)38)2-1-3-19(22)32/h1-3,6-9,11-12,14-15,24,26,31-34H,4-5,10H2,(H,30,36)(H,37,38)/t14?,15?,24-,26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
A Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human Protein kinase C gamma isozyme				J Med Chem 40: 226-35 (1997) Article DOI: 10.1021/jm960497g BindingDB Entry DOI: 10.7270/Q2J965HR
					More data for this Ligand-Target Pair
Protein kinase C (PKC) (Homo sapiens (Human))	BDBM50055666 (4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1C2CCC(C2)[C@H]1NC(=O)c1ccc(O)cc1 |TLB:22:23:28:26.25,THB:30:29:28:26.25| Show InChI InChI=1S/C29H25NO10/c31-17-8-6-13(7-9-17)27(36)30-24-14-4-5-15(10-14)26(24)40-29(39)16-11-20(33)23(21(34)12-16)25(35)22-18(28(37)38)2-1-3-19(22)32/h1-3,6-9,11-12,14-15,24,26,31-34H,4-5,10H2,(H,30,36)(H,37,38)/t14?,15?,24-,26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
A Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human Protein kinase C zeta isozyme				J Med Chem 40: 226-35 (1997) Article DOI: 10.1021/jm960497g BindingDB Entry DOI: 10.7270/Q2J965HR
					More data for this Ligand-Target Pair
PKC alpha and beta-2 (Homo sapiens (Human))	BDBM50055666 (4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1C2CCC(C2)[C@H]1NC(=O)c1ccc(O)cc1 |TLB:22:23:28:26.25,THB:30:29:28:26.25| Show InChI InChI=1S/C29H25NO10/c31-17-8-6-13(7-9-17)27(36)30-24-14-4-5-15(10-14)26(24)40-29(39)16-11-20(33)23(21(34)12-16)25(35)22-18(28(37)38)2-1-3-19(22)32/h1-3,6-9,11-12,14-15,24,26,31-34H,4-5,10H2,(H,30,36)(H,37,38)/t14?,15?,24-,26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
A Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human Protein kinase C beta 2 isozyme				J Med Chem 40: 226-35 (1997) Article DOI: 10.1021/jm960497g BindingDB Entry DOI: 10.7270/Q2J965HR
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase (PKA) (Homo sapiens (Human))	BDBM50055666 (4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1C2CCC(C2)[C@H]1NC(=O)c1ccc(O)cc1 |TLB:22:23:28:26.25,THB:30:29:28:26.25| Show InChI InChI=1S/C29H25NO10/c31-17-8-6-13(7-9-17)27(36)30-24-14-4-5-15(10-14)26(24)40-29(39)16-11-20(33)23(21(34)12-16)25(35)22-18(28(37)38)2-1-3-19(22)32/h1-3,6-9,11-12,14-15,24,26,31-34H,4-5,10H2,(H,30,36)(H,37,38)/t14?,15?,24-,26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
A Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against recombinant human cAMP-dependent Protein kinase A				J Med Chem 40: 226-35 (1997) Article DOI: 10.1021/jm960497g BindingDB Entry DOI: 10.7270/Q2J965HR
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50055666 (4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...) Show SMILES OC(=O)c1cccc(O)c1C(=O)c1c(O)cc(cc1O)C(=O)O[C@@H]1C2CCC(C2)[C@H]1NC(=O)c1ccc(O)cc1 |TLB:22:23:28:26.25,THB:30:29:28:26.25| Show InChI InChI=1S/C29H25NO10/c31-17-8-6-13(7-9-17)27(36)30-24-14-4-5-15(10-14)26(24)40-29(39)16-11-20(33)23(21(34)12-16)25(35)22-18(28(37)38)2-1-3-19(22)32/h1-3,6-9,11-12,14-15,24,26,31-34H,4-5,10H2,(H,30,36)(H,37,38)/t14?,15?,24-,26-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
A Division of Eli Lilly & Company Curated by ChEMBL					Assay Description Inhibitory concentration against recombinant human Protein kinase C delta isozyme				J Med Chem 40: 226-35 (1997) Article DOI: 10.1021/jm960497g BindingDB Entry DOI: 10.7270/Q2J965HR
					More data for this Ligand-Target Pair