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SMILES: C([C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12)N1CCN(CC1)c1ccccn1

InChI Key: InChIKey=WYVYDCVFEZZZCK-MXVIHJGJSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50055723   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50055723
PNG
(3-[4-(4-Pyridin-2-yl-piperazin-1-ylmethyl)-cyclohe...)
Show SMILES C([C@H]1CC[C@@H](CC1)c1c[nH]c2ccccc12)N1CCN(CC1)c1ccccn1 |wU:4.7,wD:1.0,(14,-4.05,;12.67,-4.82,;11.34,-4.05,;10.01,-4.82,;10.02,-6.35,;11.34,-7.12,;12.65,-6.36,;8.74,-7.2,;8.66,-8.74,;7.16,-9.15,;6.32,-7.87,;4.79,-7.64,;4.23,-6.19,;5.21,-4.98,;6.72,-5.23,;7.28,-6.65,;15.33,-4.82,;16.65,-4.02,;18,-4.79,;18.01,-6.33,;16.69,-7.12,;15.35,-6.36,;19.36,-7.09,;19.38,-8.63,;20.7,-9.38,;22.04,-8.6,;22.02,-7.06,;20.67,-6.3,)|
Show InChI InChI=1S/C24H30N4/c1-2-6-23-21(5-1)22(17-26-23)20-10-8-19(9-11-20)18-27-13-15-28(16-14-27)24-7-3-4-12-25-24/h1-7,12,17,19-20,26H,8-11,13-16,18H2/t19-,20-
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Article
PubMed
 85n/an/an/an/an/an/an/an/a



Division of Warner Lambert Company

Curated by ChEMBL


Assay Description
In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]-spiperone displacement.

J Med Chem 40: 250-9 (1997)


Article DOI: 10.1021/jm960597m
BindingDB Entry DOI: 10.7270/Q28W3CD4
More data for this
Ligand-Target Pair