BDBM50056080 (2R,3R,4S)-4-Indan-5-yl-2-(4-methoxy-phenyl)-1-[(methyl-propyl-carbamoyl)-methyl]-pyrrolidine-3-carboxylic acid::CHEMBL325444

SMILES: CCCN(C)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2CCCc2c1

InChI Key: InChIKey=LBWOFPWPPZDWOB-ARMFNRFLSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50056080   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EDNRA (RAT)	BDBM50056080 ((2R,3R,4S)-4-Indan-5-yl-2-(4-methoxy-phenyl)-1-[(m...) Show SMILES CCCN(C)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2CCCc2c1 Show InChI InChI=1S/C27H34N2O4/c1-4-14-28(2)24(30)17-29-16-23(21-9-8-18-6-5-7-20(18)15-21)25(27(31)32)26(29)19-10-12-22(33-3)13-11-19/h8-13,15,23,25-26H,4-7,14,16-17H2,1-3H3,(H,31,32)/t23-,25-,26+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards endothelin A receptor in prolactin secreting rat pituitary cells using [125I]-ET-1 as radioligand.				J Med Chem 40: 322-30 (1997) Article DOI: 10.1021/jm960077r BindingDB Entry DOI: 10.7270/Q20C4TV2
					More data for this Ligand-Target Pair
Endothelin receptor ET-B (Sus scrofa)	BDBM50056080 ((2R,3R,4S)-4-Indan-5-yl-2-(4-methoxy-phenyl)-1-[(m...) Show SMILES CCCN(C)C(=O)CN1C[C@@H]([C@H]([C@@H]1c1ccc(OC)cc1)C(O)=O)c1ccc2CCCc2c1 Show InChI InChI=1S/C27H34N2O4/c1-4-14-28(2)24(30)17-29-16-23(21-9-8-18-6-5-7-20(18)15-21)25(27(31)32)26(29)19-10-12-22(33-3)13-11-19/h8-13,15,23,25-26H,4-7,14,16-17H2,1-3H3,(H,31,32)/t23-,25-,26+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Binding affinity towards endothelin B receptor in porcine cerebellar tissue using [125I]-ET-1 as radioligand.				J Med Chem 40: 322-30 (1997) Article DOI: 10.1021/jm960077r BindingDB Entry DOI: 10.7270/Q20C4TV2
					More data for this Ligand-Target Pair