BDBM50056375 2-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propylsulfanyl}-5,6-dimethyl-3H-thieno[2,3-d]pyrimidin-4-one::CHEMBL345628

SMILES: Cc1sc2nc(SCCCN3CCN(CC3)c3ccccc3Cl)[nH]c(=O)c2c1C

InChI Key: InChIKey=QHHGYNKBCBHEBR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056375   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50056375 (2-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propylsu...) Show SMILES Cc1sc2nc(SCCCN3CCN(CC3)c3ccccc3Cl)[nH]c(=O)c2c1C Show InChI InChI=1S/C21H25ClN4OS2/c1-14-15(2)29-20-18(14)19(27)23-21(24-20)28-13-5-8-25-9-11-26(12-10-25)17-7-4-3-6-16(17)22/h3-4,6-7H,5,8-13H2,1-2H3,(H,23,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Università di Catania Curated by ChEMBL					Assay Description In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.				J Med Chem 40: 574-85 (1997) Article DOI: 10.1021/jm950866t BindingDB Entry DOI: 10.7270/Q2K64H6C
					More data for this Ligand-Target Pair