BDBM50056695 CHEMBL3326918

SMILES: CCCCCn1c(N)nc2ccccc12

InChI Key: InChIKey=ZKATYZMBJKQQKB-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056695   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Toll-like receptor 8 (Homo sapiens (Human))	BDBM50056695 (CHEMBL3326918) Show SMILES CCCCCn1c(N)nc2ccccc12 Show InChI InChI=1S/C12H17N3/c1-2-3-6-9-15-11-8-5-4-7-10(11)14-12(15)13/h4-5,7-8H,2-3,6,9H2,1H3,(H2,13,14)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.23E+3	n/a	n/a	n/a	n/a
University of Kansas Curated by ChEMBL					Assay Description Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...				J Med Chem 57: 7325-41 (2014) Article DOI: 10.1021/jm500701q BindingDB Entry DOI: 10.7270/Q2JS9S3S
					More data for this Ligand-Target Pair