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SMILES: CCCCCn1c(N)nc2c1ccc1ccccc21

InChI Key: InChIKey=QCTFAPBPHMREKD-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50056697   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Toll-like receptor 8


(Homo sapiens (Human))		BDBM50056697
PNG
(CHEMBL3326925)
Show SMILES CCCCCn1c(N)nc2c1ccc1ccccc21
Show InChI InChI=1S/C16H19N3/c1-2-3-6-11-19-14-10-9-12-7-4-5-8-13(12)15(14)18-16(19)17/h4-5,7-10H,2-3,6,11H2,1H3,(H2,17,18)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/an/an/a 3.16E+3n/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Agonist activity at human TLR8 stably expressed in HEK293 cells co-expressing secreted alkaline phosphatase assessed as NF-kappaB induction by liquid...

J Med Chem 57: 7325-41 (2014)


Article DOI: 10.1021/jm500701q
BindingDB Entry DOI: 10.7270/Q2JS9S3S
More data for this
Ligand-Target Pair