BDBM50057107 ((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-[2-(2-methyl-benzothiazol-6-yl)-ethyl]-amine::CHEMBL10304

SMILES: COc1cccc2[C@H](CN(C)CCc3ccc4nc(C)sc4c3)CCCc12

InChI Key: InChIKey=GKAAOCHBTPFZSH-SFHVURJKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50057107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50057107 (((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylm...) Show SMILES COc1cccc2[C@H](CN(C)CCc3ccc4nc(C)sc4c3)CCCc12 Show InChI InChI=1S/C23H28N2OS/c1-16-24-21-11-10-17(14-23(21)27-16)12-13-25(2)15-18-6-4-8-20-19(18)7-5-9-22(20)26-3/h5,7,9-11,14,18H,4,6,8,12-13,15H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	86.7	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Park Curated by ChEMBL					Assay Description Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortex				J Med Chem 40: 1049-62 (1997) Article DOI: 10.1021/jm960723m BindingDB Entry DOI: 10.7270/Q2CF9P6W
					More data for this Ligand-Target Pair