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SMILES: COc1cccc2[C@H](CN(C)CCc3ccc4CN(Cc4c3)S(=O)(=O)C(F)(F)F)CCCc12

InChI Key: InChIKey=MQUVXEKZVIEFPU-IBGZPJMESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50057123   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50057123
PNG
(((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylm...)
Show SMILES COc1cccc2[C@H](CN(C)CCc3ccc4CN(Cc4c3)S(=O)(=O)C(F)(F)F)CCCc12
Show InChI InChI=1S/C24H29F3N2O3S/c1-28(14-19-5-3-7-22-21(19)6-4-8-23(22)32-2)12-11-17-9-10-18-15-29(16-20(18)13-17)33(30,31)24(25,26)27/h4,6,8-10,13,19H,3,5,7,11-12,14-16H2,1-2H3/t19-/m0/s1
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 59.8n/an/an/an/an/an/a



Abbott Park

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortex

J Med Chem 40: 1049-62 (1997)


Article DOI: 10.1021/jm960723m
BindingDB Entry DOI: 10.7270/Q2CF9P6W
More data for this
Ligand-Target Pair