BDBM50057129 (2-Indan-5-yl-ethyl)-((R)-5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-amine::CHEMBL10409

SMILES: COc1cccc2[C@H](CN(C)CCc3ccc4CCCc4c3)CCCc12

InChI Key: InChIKey=UTFOJGQFAPRIEA-NRFANRHFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50057129   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50057129 ((2-Indan-5-yl-ethyl)-((R)-5-methoxy-1,2,3,4-tetrah...) Show SMILES COc1cccc2[C@H](CN(C)CCc3ccc4CCCc4c3)CCCc12 Show InChI InChI=1S/C24H31NO/c1-25(15-14-18-12-13-19-6-3-7-20(19)16-18)17-21-8-4-10-23-22(21)9-5-11-24(23)26-2/h5,9,11-13,16,21H,3-4,6-8,10,14-15,17H2,1-2H3/t21-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20.5	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Park Curated by ChEMBL					Assay Description Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortex				J Med Chem 40: 1049-62 (1997) Article DOI: 10.1021/jm960723m BindingDB Entry DOI: 10.7270/Q2CF9P6W
					More data for this Ligand-Target Pair