BDBM50057131 6-{2-[((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-methyl-amino]-ethyl}-3H-benzooxazol-2-one::CHEMBL10115

SMILES: COc1cccc2[C@H](CN(C)CCc3ccc4[nH]c(=O)oc4c3)CCCc12

InChI Key: InChIKey=CNKACCQCBCIPTI-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50057131   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50057131 (6-{2-[((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen...) Show SMILES COc1cccc2[C@H](CN(C)CCc3ccc4[nH]c(=O)oc4c3)CCCc12 Show InChI InChI=1S/C22H26N2O3/c1-24(12-11-15-9-10-19-21(13-15)27-22(25)23-19)14-16-5-3-7-18-17(16)6-4-8-20(18)26-2/h4,6,8-10,13,16H,3,5,7,11-12,14H2,1-2H3,(H,23,25)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19.4	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Park Curated by ChEMBL					Assay Description Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortex				J Med Chem 40: 1049-62 (1997) Article DOI: 10.1021/jm960723m BindingDB Entry DOI: 10.7270/Q2CF9P6W
					More data for this Ligand-Target Pair