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SMILES: COc1cccc2[C@H](CN(C)CCc3ccc4cccnc4c3)CCCc12

InChI Key: InChIKey=VCXNDBFIRNSLCW-FQEVSTJZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50057145   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium-dependent serotonin transporter


(Rattus norvegicus (rat))		BDBM50057145
PNG
(((R)-5-Methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylm...)
Show SMILES COc1cccc2[C@H](CN(C)CCc3ccc4cccnc4c3)CCCc12
Show InChI InChI=1S/C24H28N2O/c1-26(15-13-18-11-12-19-7-5-14-25-23(19)16-18)17-20-6-3-9-22-21(20)8-4-10-24(22)27-2/h4-5,7-8,10-12,14,16,20H,3,6,9,13,15,17H2,1-2H3/t20-/m0/s1
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Article
PubMed
n/an/a 18.1n/an/an/an/an/an/a



Abbott Park

Curated by ChEMBL


Assay Description
Inhibition of uptake of [3H]-5-HT in synaptosomes from rat cortex

J Med Chem 40: 1049-62 (1997)


Article DOI: 10.1021/jm960723m
BindingDB Entry DOI: 10.7270/Q2CF9P6W
More data for this
Ligand-Target Pair