BDBM50057242 4-Hydroxy-3-{(E)-3-[3-(quinolin-2-ylmethoxy)-phenyl]-acryloyl}-benzoic acid::4-hydroxy-3-(3-(3-(quinolin-2-ylmethoxy)phenyl)acryloyl)benzoic acid::CHEMBL276879

SMILES: OC(=O)c1ccc(O)c(c1)C(=O)\C=C\c1cccc(OCc2ccc3ccccc3n2)c1

InChI Key: InChIKey=WOOGNRDKJXUFCT-XYOKQWHBSA-N

Data: 1 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50057242   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50057242 (4-Hydroxy-3-{(E)-3-[3-(quinolin-2-ylmethoxy)-pheny...) Show SMILES OC(=O)c1ccc(O)c(c1)C(=O)\C=C\c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C26H19NO5/c28-24(22-15-19(26(30)31)10-13-25(22)29)12-8-17-4-3-6-21(14-17)32-16-20-11-9-18-5-1-2-7-23(18)27-20/h1-15,29H,16H2,(H,30,31)/b12-8+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	609	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Curated by ChEMBL					Assay Description Displacement of [3H]LTD4 from Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				J Med Chem 40: 1075-89 (1997) Article DOI: 10.1021/jm960628d BindingDB Entry DOI: 10.7270/Q25141XJ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50057242 (4-Hydroxy-3-{(E)-3-[3-(quinolin-2-ylmethoxy)-pheny...) Show SMILES OC(=O)c1ccc(O)c(c1)C(=O)\C=C\c1cccc(OCc2ccc3ccccc3n2)c1 Show InChI InChI=1S/C26H19NO5/c28-24(22-15-19(26(30)31)10-13-25(22)29)12-8-17-4-3-6-21(14-17)32-16-20-11-9-18-5-1-2-7-23(18)27-20/h1-15,29H,16H2,(H,30,31)/b12-8+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	609	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Antagonist activity at CysLT1 receptor in human dU937 cells assessed as inhibition of LTD4-induced increase of calcium level treated 30 mins before L...				Bioorg Med Chem 18: 5519-27 (2010) Article DOI: 10.1016/j.bmc.2010.06.047 BindingDB Entry DOI: 10.7270/Q26D5TZ0
					More data for this Ligand-Target Pair