BDBM50058036 CHEMBL3330790

SMILES: Cl.CNCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC)c2sccc12

InChI Key: InChIKey=IWFNYBFNXUYKLW-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50058036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058036 (CHEMBL3330790) Show SMILES Cl.CNCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC)c2sccc12 Show InChI InChI=1S/C22H24N4O2S.ClH/c1-23-8-10-25-18-15-7-12-29-22(15)19(26-11-9-24-2)17-16(18)20(27)13-5-3-4-6-14(13)21(17)28;/h3-7,12,23-26H,8-11H2,1-2H3;1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate by Real-time ...				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50058036 (CHEMBL3330790) Show SMILES Cl.CNCCNc1c2C(=O)c3ccccc3C(=O)c2c(NCCNC)c2sccc12 Show InChI InChI=1S/C22H24N4O2S.ClH/c1-23-8-10-25-18-15-7-12-29-22(15)19(26-11-9-24-2)17-16(18)20(27)13-5-3-4-6-14(13)21(17)28;/h3-7,12,23-26H,8-11H2,1-2H3;1H	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Russian Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of human telomerase transfected in human HEK293T cells assessed as DNA extension using 5'-d(AATCCGTCGAGCAGAGTT)-3' substrate				Eur J Med Chem 85: 605-14 (2014) Article DOI: 10.1016/j.ejmech.2014.08.030 BindingDB Entry DOI: 10.7270/Q2FX7C4Z
					More data for this Ligand-Target Pair