BDBM50058807 CHEMBL3329520

SMILES: C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1Cl)c1ccccn1

InChI Key: InChIKey=CUEHPRFMGPZGQA-UFFVCSGVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50058807   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cruzipain (Trypanosoma cruzi)	BDBM50058807 (CHEMBL3329520) Show SMILES C\C(=N/Nc1nc(cs1)-c1ccc(Cl)cc1Cl)c1ccccn1 Show InChI InChI=1S/C16H12Cl2N4S/c1-10(14-4-2-3-7-19-14)21-22-16-20-15(9-23-16)12-6-5-11(17)8-13(12)18/h2-9H,1H3,(H,20,22)/b21-10+	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Pernambuco Curated by ChEMBL					Assay Description Inhibition of recombinant Trypanosoma cruzi cruzain using Z-Phe-Argaminomethylcoumarin as fluorogenic substrate preincubated for 10 mins before subst...				Eur J Med Chem 86: 48-59 (2014) Article DOI: 10.1016/j.ejmech.2014.08.012 BindingDB Entry DOI: 10.7270/Q2W097M2
					More data for this Ligand-Target Pair