null

SMILES: COc1ccc(cc1OC)S(=O)(=O)N1C(=O)CN(C1=O)c1ccc(C)c(C)c1

InChI Key: InChIKey=KLKUYQFIUYGVGO-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50058990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50058990 (3-(3,4-Dimethoxy-benzenesulfonyl)-1-(3,4-dimethyl-...) Show SMILES COc1ccc(cc1OC)S(=O)(=O)N1C(=O)CN(C1=O)c1ccc(C)c(C)c1 Show InChI InChI=1S/C19H20N2O6S/c1-12-5-6-14(9-13(12)2)20-11-18(22)21(19(20)23)28(24,25)15-7-8-16(26-3)17(10-15)27-4/h5-10H,11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human heart chymase in vitro.				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair
Cathepsin G (Homo sapiens (Human))	BDBM50058990 (3-(3,4-Dimethoxy-benzenesulfonyl)-1-(3,4-dimethyl-...) Show SMILES COc1ccc(cc1OC)S(=O)(=O)N1C(=O)CN(C1=O)c1ccc(C)c(C)c1 Show InChI InChI=1S/C19H20N2O6S/c1-12-5-6-14(9-13(12)2)20-11-18(22)21(19(20)23)28(24,25)15-7-8-16(26-3)17(10-15)27-4/h5-10H,11H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against human neutrophil cathepsin G.				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair
Chymotrypsinogen A (Bos taurus (bovine))	BDBM50058990 (3-(3,4-Dimethoxy-benzenesulfonyl)-1-(3,4-dimethyl-...) Show SMILES COc1ccc(cc1OC)S(=O)(=O)N1C(=O)CN(C1=O)c1ccc(C)c(C)c1 Show InChI InChI=1S/C19H20N2O6S/c1-12-5-6-14(9-13(12)2)20-11-18(22)21(19(20)23)28(24,25)15-7-8-16(26-3)17(10-15)27-4/h5-10H,11H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Suntory Ltd. Curated by ChEMBL					Assay Description Inhibitory activity against bovine pancreas alpha-chymotrypsin in vitro				J Med Chem 40: 2156-63 (1997) Article DOI: 10.1021/jm960793t BindingDB Entry DOI: 10.7270/Q2QJ7GDG
					More data for this Ligand-Target Pair