BDBM50059120 5,7-Dimethyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one::CHEMBL49330

SMILES: Cc1ccc(cc1)-c1cc(O)c2c(C)cc(C)nc2n1

InChI Key: InChIKey=JMIJQUSJCPEKAN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059120   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin (Sus scrofa (Pig))	BDBM50059120 (5,7-Dimethyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one ...) Show SMILES Cc1ccc(cc1)-c1cc(O)c2c(C)cc(C)nc2n1 Show InChI InChI=1S/C17H16N2O/c1-10-4-6-13(7-5-10)14-9-15(20)16-11(2)8-12(3)18-17(16)19-14/h4-9H,1-3H3,(H,18,19,20)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of tubulin polymerization interacting at the colchicine binding site.				J Med Chem 43: 167-76 (2000) BindingDB Entry DOI: 10.7270/Q2CV4JZB
					More data for this Ligand-Target Pair
Tubulin (Bos taurus)	BDBM50059120 (5,7-Dimethyl-2-p-tolyl-1H-[1,8]naphthyridin-4-one ...) Show SMILES Cc1ccc(cc1)-c1cc(O)c2c(C)cc(C)nc2n1 Show InChI InChI=1S/C17H16N2O/c1-10-4-6-13(7-5-10)14-9-15(20)16-11(2)8-12(3)18-17(16)19-14/h4-9H,1-3H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill 27599 Curated by ChEMBL					Assay Description Inhibition of bovine tubulin polymerization				J Med Chem 40: 2266-75 (1997) Article DOI: 10.1021/jm960858s BindingDB Entry DOI: 10.7270/Q26M35ZF
					More data for this Ligand-Target Pair