BDBM50059130 CHEMBL74992::{7-[(1H-Benzoimidazol-2-ylmethyl)-carbamoyl]-4-methyl-3-oxo-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepin-2-yl}-acetic acid

SMILES: CN1Cc2cc(ccc2NC(CC(O)=O)C1=O)C(=O)NCc1nc2ccccc2[nH]1

InChI Key: InChIKey=WYYLCRHWQCODSD-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50059130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ITGAV/ITGB3 (Homo sapiens (Human))	BDBM50059130 (CHEMBL74992 | {7-[(1H-Benzoimidazol-2-ylmethyl)-ca...) Show SMILES CN1Cc2cc(ccc2NC(CC(O)=O)C1=O)C(=O)NCc1nc2ccccc2[nH]1 Show InChI InChI=1S/C21H21N5O4/c1-26-11-13-8-12(6-7-14(13)23-17(21(26)30)9-19(27)28)20(29)22-10-18-24-15-4-2-3-5-16(15)25-18/h2-8,17,23H,9-11H2,1H3,(H,22,29)(H,24,25)(H,27,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Affinity for vitronectin receptor, integrin alphaV-beta3				J Med Chem 40: 2289-92 (1997) Article DOI: 10.1021/jm970205r BindingDB Entry DOI: 10.7270/Q22V2F74
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50059130 (CHEMBL74992 | {7-[(1H-Benzoimidazol-2-ylmethyl)-ca...) Show SMILES CN1Cc2cc(ccc2NC(CC(O)=O)C1=O)C(=O)NCc1nc2ccccc2[nH]1 Show InChI InChI=1S/C21H21N5O4/c1-26-11-13-8-12(6-7-14(13)23-17(21(26)30)9-19(27)28)20(29)22-10-18-24-15-4-2-3-5-16(15)25-18/h2-8,17,23H,9-11H2,1H3,(H,22,29)(H,24,25)(H,27,28)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Affinity for platelet fibrinogen receptor, integrin alpha IIb/beta3				J Med Chem 40: 2289-92 (1997) Article DOI: 10.1021/jm970205r BindingDB Entry DOI: 10.7270/Q22V2F74
					More data for this Ligand-Target Pair