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BDBM50059778 (2R,6S)-3-((S)-2-Methoxy-propyl)-6,11,11-trimethyl-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol::CHEMBL329980

SMILES: CO[C@@H](C)CN1CC[C@@]2(C)c3cc(O)ccc3C[C@@H]1C2(C)C

InChI Key: InChIKey=ZZDBWKNXQCIZFX-IRWQIABSSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50059778   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mu-type opioid receptor


(Rattus norvegicus (rat))		BDBM50059778
PNG
((2R,6S)-3-((S)-2-Methoxy-propyl)-6,11,11-trimethyl...)
Show SMILES CO[C@@H](C)CN1CC[C@@]2(C)c3cc(O)ccc3C[C@@H]1C2(C)C |TLB:4:5:19:10.16.17|
Show InChI InChI=1S/C19H29NO2/c1-13(22-5)12-20-9-8-19(4)16-11-15(21)7-6-14(16)10-17(20)18(19,2)3/h6-7,11,13,17,21H,8-10,12H2,1-5H3/t13-,17+,19-/m0/s1
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Similars
Article
PubMed
 1.60n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-dihydromorphine binding to opioid receptor mu 1 in rat brain cortical membranes.

J Med Chem 40: 2922-30 (1997)


Article DOI: 10.1021/jm970131j
BindingDB Entry DOI: 10.7270/Q2W66JW9
More data for this
Ligand-Target Pair