BDBM50060309 2-{4-[4-(4-carbamimidoyl-phenyl)-thiazol-2-ylamino]-piperidin-1-yl}-propionic acid::CHEMBL333633

SMILES: CC(N1CCC(CC1)Nc1nc(cs1)-c1ccc(cc1)C(N)=N)C(O)=O

InChI Key: InChIKey=GKZGZOCUWIMUGH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50060309   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50060309 (2-{4-[4-(4-carbamimidoyl-phenyl)-thiazol-2-ylamino...) Show SMILES CC(N1CCC(CC1)Nc1nc(cs1)-c1ccc(cc1)C(N)=N)C(O)=O Show InChI InChI=1S/C18H23N5O2S/c1-11(17(24)25)23-8-6-14(7-9-23)21-18-22-15(10-26-18)12-2-4-13(5-3-12)16(19)20/h2-5,10-11,14H,6-9H2,1H3,(H3,19,20)(H,21,22)(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi Recherche Curated by ChEMBL					Assay Description In vitro inhibition of ADP-induced (2.5 microM) human platelet aggregation.				J Med Chem 40: 3393-401 (1997) Article DOI: 10.1021/jm970240y BindingDB Entry DOI: 10.7270/Q2FX78J3
					More data for this Ligand-Target Pair