BDBM50061222 3-Cyclohexyl-N-((R)-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-propionamide::CHEMBL340353

SMILES: CN1c2ccccc2C(=N[C@@H](NC(=O)CCC2CCCCC2)C1=O)c1ccccc1

InChI Key: InChIKey=FLGHLGGIQDOQPD-XMMPIXPASA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50061222   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor (Homo sapiens (Human))	BDBM50061222 (3-Cyclohexyl-N-((R)-1-methyl-2-oxo-5-phenyl-2,3-di...) Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)CCC2CCCCC2)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C25H29N3O2/c1-28-21-15-9-8-14-20(21)23(19-12-6-3-7-13-19)27-24(25(28)30)26-22(29)17-16-18-10-4-2-5-11-18/h3,6-9,12-15,18,24H,2,4-5,10-11,16-17H2,1H3,(H,26,29)/t24-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Half maximal inhibition of binding of [125I]-CCK-8 to Cholecystokinin type B receptor in guinea pig cerebral cortex.				J Med Chem 40: 3865-8 (1998) Article DOI: 10.1021/jm970517u BindingDB Entry DOI: 10.7270/Q2Q81C6H
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50061222 (3-Cyclohexyl-N-((R)-1-methyl-2-oxo-5-phenyl-2,3-di...) Show SMILES CN1c2ccccc2C(=N[C@@H](NC(=O)CCC2CCCCC2)C1=O)c1ccccc1 |c:9| Show InChI InChI=1S/C25H29N3O2/c1-28-21-15-9-8-14-20(21)23(19-12-6-3-7-13-19)27-24(25(28)30)26-22(29)17-16-18-10-4-2-5-11-18/h3,6-9,12-15,18,24H,2,4-5,10-11,16-17H2,1H3,(H,26,29)/t24-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of Ikr current in isolated guinea pig myocytes during a 0.5 s voltage clamp step from -50 to -10 mV.				J Med Chem 40: 3865-8 (1998) Article DOI: 10.1021/jm970517u BindingDB Entry DOI: 10.7270/Q2Q81C6H
					More data for this Ligand-Target Pair