null
SMILES: COC(=O)CC1=C(Cc2ccccc2)CC2C(Cc3ccccc3)CC1N2C
InChI Key: InChIKey=UPUHZXXATZMRQT-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50061952![]() ((3,6-Dibenzyl-8-methyl-8-aza-bicyclo[3.2.1]oct-2-e...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 4.79E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Binding affinity to dopamine transporter (DAT) using [3H]WIN-35428 as a radioligand | J Med Chem 43: 4151-9 (2000) Article DOI: 10.1021/jm990472s BindingDB Entry DOI: 10.7270/Q2PK0JWZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50061952![]() ((3,6-Dibenzyl-8-methyl-8-aza-bicyclo[3.2.1]oct-2-e...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 4.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of New Orleans Curated by ChEMBL | Assay Description Displacement of [3H]WIN-35428 from dopamine transporter in rat caudate putamen tissue | J Med Chem 40: 4406-14 (1998) Article DOI: 10.1021/jm970549h BindingDB Entry DOI: 10.7270/Q22R3SBZ | |||||||||||
More data for this Ligand-Target Pair |