BDBM50062474 2,N-Dibenzyl-N'-hydroxy-malonamide::2N-dibenzyl-N'-hydroxy-malonamide::CHEMBL113827::N1,2-dibenzyl-N3-hydroxymalonamide

SMILES: ONC(=O)C(Cc1ccccc1)C(=O)NCc1ccccc1

InChI Key: InChIKey=WKIMWNKNDQXNCK-UHFFFAOYSA-N

Data: 2 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50062474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutrophil collagenase (Homo sapiens (Human))	BDBM50062474 (2,N-Dibenzyl-N'-hydroxy-malonamide | 2N-dibenzyl-N...) Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C17H18N2O3/c20-16(18-12-14-9-5-2-6-10-14)15(17(21)19-22)11-13-7-3-1-4-8-13/h1-10,15,22H,11-12H2,(H,18,20)(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pomona College Curated by ChEMBL					Assay Description Inhibition of MMP8				Bioorg Med Chem 15: 2223-68 (2007) Article DOI: 10.1016/j.bmc.2007.01.011 BindingDB Entry DOI: 10.7270/Q2571DBD
					More data for this Ligand-Target Pair
Neutrophil collagenase (Homo sapiens (Human))	BDBM50062474 (2,N-Dibenzyl-N'-hydroxy-malonamide | 2N-dibenzyl-N...) Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C17H18N2O3/c20-16(18-12-14-9-5-2-6-10-14)15(17(21)19-22)11-13-7-3-1-4-8-13/h1-10,15,22H,11-12H2,(H,18,20)(H,19,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut für Biochemie Curated by ChEMBL					Assay Description Inhibition of Matrix metalloproteinase-8 (Human neutrophil collagenase, MMP-8)				J Med Chem 41: 339-45 (1998) Article DOI: 10.1021/jm9706426 BindingDB Entry DOI: 10.7270/Q2639NWF
					More data for this Ligand-Target Pair
Zinc aminopeptidase (Plasmodium falciparum (isolate FcB1 / Columbia))	BDBM50062474 (2,N-Dibenzyl-N'-hydroxy-malonamide | 2N-dibenzyl-N...) Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C17H18N2O3/c20-16(18-12-14-9-5-2-6-10-14)15(17(21)19-22)11-13-7-3-1-4-8-13/h1-10,15,22H,11-12H2,(H,18,20)(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
Inserm Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum FcB1 M1 aminopeptidase				J Med Chem 50: 1322-34 (2007) Article DOI: 10.1021/jm061169b BindingDB Entry DOI: 10.7270/Q2M908B3
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50062474 (2,N-Dibenzyl-N'-hydroxy-malonamide | 2N-dibenzyl-N...) Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C17H18N2O3/c20-16(18-12-14-9-5-2-6-10-14)15(17(21)19-22)11-13-7-3-1-4-8-13/h1-10,15,22H,11-12H2,(H,18,20)(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Lille 2 Curated by ChEMBL					Assay Description Inhibition of microsomal neural aminopeptidase in pig kidney				Bioorg Med Chem 15: 63-76 (2006) Article DOI: 10.1016/j.bmc.2006.10.010 BindingDB Entry DOI: 10.7270/Q23F4P9V
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50062474 (2,N-Dibenzyl-N'-hydroxy-malonamide | 2N-dibenzyl-N...) Show SMILES ONC(=O)C(Cc1ccccc1)C(=O)NCc1ccccc1 Show InChI InChI=1S/C17H18N2O3/c20-16(18-12-14-9-5-2-6-10-14)15(17(21)19-22)11-13-7-3-1-4-8-13/h1-10,15,22H,11-12H2,(H,18,20)(H,19,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Inhibition of porcine kidney microsomal neutral aminopeptidase using Leu-pNA as substrate preincubated for 10 mins				J Med Chem 55: 10909-17 (2012) Article DOI: 10.1021/jm301506h BindingDB Entry DOI: 10.7270/Q2Z60Q6R
					More data for this Ligand-Target Pair