null

SMILES: CCCCCCSc1nsnc1OC1CN2CCC1CC2

InChI Key: InChIKey=QFNZGJLFACGDSQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50062593   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50062593 (3-(4-Hexylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-az...) Show SMILES CCCCCCSc1nsnc1OC1CN2CCC1CC2 |(7.81,-17,;8.96,-15.97,;8.66,-14.47,;9.8,-13.45,;9.5,-11.93,;10.64,-10.9,;10.33,-9.4,;11.48,-8.38,;13,-8.7,;13.77,-7.35,;12.72,-6.2,;11.34,-6.83,;10,-6.06,;8.66,-6.83,;8.66,-8.38,;7.32,-9.14,;6.01,-8.38,;6.01,-6.83,;7.32,-6.05,;6.57,-7.39,;8.1,-7.79,)| Show InChI InChI=1S/C15H25N3OS2/c1-2-3-4-5-10-20-15-14(16-21-17-15)19-13-11-18-8-6-12(13)7-9-18/h12-13H,2-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-Pirenzepine (Pz) radioligand in rat hippocampus membranes.				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50062593 (3-(4-Hexylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-az...) Show SMILES CCCCCCSc1nsnc1OC1CN2CCC1CC2 |(7.81,-17,;8.96,-15.97,;8.66,-14.47,;9.8,-13.45,;9.5,-11.93,;10.64,-10.9,;10.33,-9.4,;11.48,-8.38,;13,-8.7,;13.77,-7.35,;12.72,-6.2,;11.34,-6.83,;10,-6.06,;8.66,-6.83,;8.66,-8.38,;7.32,-9.14,;6.01,-8.38,;6.01,-6.83,;7.32,-6.05,;6.57,-7.39,;8.1,-7.79,)| Show InChI InChI=1S/C15H25N3OS2/c1-2-3-4-5-10-20-15-14(16-21-17-15)19-13-11-18-8-6-12(13)7-9-18/h12-13H,2-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Binding affinity for muscarinic acetylcholine receptor M1 using [3H]-oxotremorine-M (Oxo-M) radioligand in rat hippocampus membranes				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50062593 (3-(4-Hexylsulfanyl-[1,2,5]thiadiazol-3-yloxy)-1-az...) Show SMILES CCCCCCSc1nsnc1OC1CN2CCC1CC2 |(7.81,-17,;8.96,-15.97,;8.66,-14.47,;9.8,-13.45,;9.5,-11.93,;10.64,-10.9,;10.33,-9.4,;11.48,-8.38,;13,-8.7,;13.77,-7.35,;12.72,-6.2,;11.34,-6.83,;10,-6.06,;8.66,-6.83,;8.66,-8.38,;7.32,-9.14,;6.01,-8.38,;6.01,-6.83,;7.32,-6.05,;6.57,-7.39,;8.1,-7.79,)| Show InChI InChI=1S/C15H25N3OS2/c1-2-3-4-5-10-20-15-14(16-21-17-15)19-13-11-18-8-6-12(13)7-9-18/h12-13H,2-11H2,1H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	225	n/a	n/a	n/a	n/a
Lilly Research Laboratories Curated by ChEMBL					Assay Description Effective concentration required for stimulation of phosphoinositol (PI) hydrolysis in the A9 L cell line transfected with the Muscarinic acetylcholi...				J Med Chem 41: 379-92 (1998) Article DOI: 10.1021/jm970125n BindingDB Entry DOI: 10.7270/Q2SX6CBC
					More data for this Ligand-Target Pair