BDBM50063096 1,8,8,9-Tetramethyl-4-trifluoromethyl-6,7,8,9-tetrahydro-1H-pyrido[3,2-g]quinolin-2-one::CHEMBL435651

SMILES: CN1c2cc3n(C)c(=O)cc(c3cc2CCC1(C)C)C(F)(F)F

InChI Key: InChIKey=MRXBSJZWWYDSFJ-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50063096 (1,8,8,9-Tetramethyl-4-trifluoromethyl-6,7,8,9-tetr...) Show SMILES CN1c2cc3n(C)c(=O)cc(c3cc2CCC1(C)C)C(F)(F)F Show InChI InChI=1S/C17H19F3N2O/c1-16(2)6-5-10-7-11-12(17(18,19)20)8-15(23)21(3)14(11)9-13(10)22(16)4/h7-9H,5-6H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity for human androgen receptor in transiently-transfected COS-1 cells.				J Med Chem 41: 623-39 (1998) Article DOI: 10.1021/jm970699s BindingDB Entry DOI: 10.7270/Q2VM4CZ6
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50063096 (1,8,8,9-Tetramethyl-4-trifluoromethyl-6,7,8,9-tetr...) Show SMILES CN1c2cc3n(C)c(=O)cc(c3cc2CCC1(C)C)C(F)(F)F Show InChI InChI=1S/C17H19F3N2O/c1-16(2)6-5-10-7-11-12(17(18,19)20)8-15(23)21(3)14(11)9-13(10)22(16)4/h7-9H,5-6H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against human androgen receptor (hAR) in co-transfected CV-1 cells.				J Med Chem 41: 623-39 (1998) Article DOI: 10.1021/jm970699s BindingDB Entry DOI: 10.7270/Q2VM4CZ6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50063096 (1,8,8,9-Tetramethyl-4-trifluoromethyl-6,7,8,9-tetr...) Show SMILES CN1c2cc3n(C)c(=O)cc(c3cc2CCC1(C)C)C(F)(F)F Show InChI InChI=1S/C17H19F3N2O/c1-16(2)6-5-10-7-11-12(17(18,19)20)8-15(23)21(3)14(11)9-13(10)22(16)4/h7-9H,5-6H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against human progesterone receptor B (hPR-B) in co-transfected CV-1 cells.				J Med Chem 41: 623-39 (1998) Article DOI: 10.1021/jm970699s BindingDB Entry DOI: 10.7270/Q2VM4CZ6
					More data for this Ligand-Target Pair