null

SMILES: Cn1c2cc3N4CCCC4(C)CCc3cc2c(cc1=O)C(F)(F)F

InChI Key: InChIKey=ORGKYZVJZBDUGT-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063118   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen receptor (Homo sapiens (Human))	BDBM50063118 (3a,10-Dimethyl-7-trifluoromethyl-1,2,3a,4,5,10-hex...) Show SMILES Cn1c2cc3N4CCCC4(C)CCc3cc2c(cc1=O)C(F)(F)F Show InChI InChI=1S/C18H19F3N2O/c1-17-5-3-7-23(17)14-10-15-12(8-11(14)4-6-17)13(18(19,20)21)9-16(24)22(15)2/h8-10H,3-7H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	78	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Binding affinity for human androgen receptor in transiently-transfected COS-1 cells.				J Med Chem 41: 623-39 (1998) Article DOI: 10.1021/jm970699s BindingDB Entry DOI: 10.7270/Q2VM4CZ6
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50063118 (3a,10-Dimethyl-7-trifluoromethyl-1,2,3a,4,5,10-hex...) Show SMILES Cn1c2cc3N4CCCC4(C)CCc3cc2c(cc1=O)C(F)(F)F Show InChI InChI=1S/C18H19F3N2O/c1-17-5-3-7-23(17)14-10-15-12(8-11(14)4-6-17)13(18(19,20)21)9-16(24)22(15)2/h8-10H,3-7H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against human progesterone receptor B (hPR-B) in co-transfected CV-1 cells.				J Med Chem 41: 623-39 (1998) Article DOI: 10.1021/jm970699s BindingDB Entry DOI: 10.7270/Q2VM4CZ6
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50063118 (3a,10-Dimethyl-7-trifluoromethyl-1,2,3a,4,5,10-hex...) Show SMILES Cn1c2cc3N4CCCC4(C)CCc3cc2c(cc1=O)C(F)(F)F Show InChI InChI=1S/C18H19F3N2O/c1-17-5-3-7-23(17)14-10-15-12(8-11(14)4-6-17)13(18(19,20)21)9-16(24)22(15)2/h8-10H,3-7H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Antagonistic activity against human androgen receptor (hAR) in co-transfected CV-1 cells.				J Med Chem 41: 623-39 (1998) Article DOI: 10.1021/jm970699s BindingDB Entry DOI: 10.7270/Q2VM4CZ6
					More data for this Ligand-Target Pair