null

SMILES: C(CN1CCc2ccccc2C1)[C@H]1CC[C@@H](CC1)Nc1ncccn1

InChI Key: InChIKey=BEKYXSCBRPYPCE-IRJFHVNHSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50063278   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50063278 (CHEMBL165440 | {4-[2-(3,4-Dihydro-1H-isoquinolin-2...) Show SMILES C(CN1CCc2ccccc2C1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:15.20,wD:12.13,(10.31,-5.42,;11.15,-6.7,;12.69,-6.63,;13.39,-5.25,;14.9,-5.18,;15.74,-6.44,;17.26,-6.35,;18.12,-7.61,;17.47,-9.01,;15.93,-9.12,;15.07,-7.84,;13.53,-7.91,;8.77,-5.49,;7.93,-4.2,;6.42,-4.27,;5.7,-5.65,;6.53,-6.93,;8.07,-6.86,;4.16,-5.72,;3.32,-4.41,;4.04,-3.06,;3.2,-1.76,;1.66,-1.83,;.96,-3.2,;1.8,-4.51,)| Show InChI InChI=1S/C21H28N4/c1-2-5-19-16-25(15-11-18(19)4-1)14-10-17-6-8-20(9-7-17)24-21-22-12-3-13-23-21/h1-5,12-13,17,20H,6-11,14-16H2,(H,22,23,24)/t17-,20-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cells				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50063278 (CHEMBL165440 | {4-[2-(3,4-Dihydro-1H-isoquinolin-2...) Show SMILES C(CN1CCc2ccccc2C1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:15.20,wD:12.13,(10.31,-5.42,;11.15,-6.7,;12.69,-6.63,;13.39,-5.25,;14.9,-5.18,;15.74,-6.44,;17.26,-6.35,;18.12,-7.61,;17.47,-9.01,;15.93,-9.12,;15.07,-7.84,;13.53,-7.91,;8.77,-5.49,;7.93,-4.2,;6.42,-4.27,;5.7,-5.65,;6.53,-6.93,;8.07,-6.86,;4.16,-5.72,;3.32,-4.41,;4.04,-3.06,;3.2,-1.76,;1.66,-1.83,;.96,-3.2,;1.8,-4.51,)| Show InChI InChI=1S/C21H28N4/c1-2-5-19-16-25(15-11-18(19)4-1)14-10-17-6-8-20(9-7-17)24-21-22-12-3-13-23-21/h1-5,12-13,17,20H,6-11,14-16H2,(H,22,23,24)/t17-,20-	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50063278 (CHEMBL165440 | {4-[2-(3,4-Dihydro-1H-isoquinolin-2...) Show SMILES C(CN1CCc2ccccc2C1)[C@H]1CC[C@@H](CC1)Nc1ncccn1 |wU:15.20,wD:12.13,(10.31,-5.42,;11.15,-6.7,;12.69,-6.63,;13.39,-5.25,;14.9,-5.18,;15.74,-6.44,;17.26,-6.35,;18.12,-7.61,;17.47,-9.01,;15.93,-9.12,;15.07,-7.84,;13.53,-7.91,;8.77,-5.49,;7.93,-4.2,;6.42,-4.27,;5.7,-5.65,;6.53,-6.93,;8.07,-6.86,;4.16,-5.72,;3.32,-4.41,;4.04,-3.06,;3.2,-1.76,;1.66,-1.83,;.96,-3.2,;1.8,-4.51,)| Show InChI InChI=1S/C21H28N4/c1-2-5-19-16-25(15-11-18(19)4-1)14-10-17-6-8-20(9-7-17)24-21-22-12-3-13-23-21/h1-5,12-13,17,20H,6-11,14-16H2,(H,22,23,24)/t17-,20-	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2				J Med Chem 41: 760-71 (1998) Article DOI: 10.1021/jm9707378 BindingDB Entry DOI: 10.7270/Q20G3J97
					More data for this Ligand-Target Pair