BDBM50063627 CHEMBL9354::N-(3-ethylesterbenzoicacid)-2-[3,4-dihydro-3-[(3-methoxy)-phenyl]-4-oxo-2-quinazolinyl]hydrazinecarboxamide

SMILES: CCOC(=O)c1cccc(NC(=O)NNc2nc3ccccc3c(=O)n2-c2cccc(OC)c2)c1

InChI Key: InChIKey=XJZFZYQZLMGXDL-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50063627   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cholecystokinin receptor type A (RAT)	BDBM50063627 (CHEMBL9354 | N-(3-ethylesterbenzoicacid)-2-[3,4-di...) Show SMILES CCOC(=O)c1cccc(NC(=O)NNc2nc3ccccc3c(=O)n2-c2cccc(OC)c2)c1 Show InChI InChI=1S/C25H23N5O5/c1-3-35-23(32)16-8-6-9-17(14-16)26-25(33)29-28-24-27-21-13-5-4-12-20(21)22(31)30(24)18-10-7-11-19(15-18)34-2/h4-15H,3H2,1-2H3,(H,27,28)(H2,26,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Binding affinity towards Cholecystokinin type A receptor (CCK-A) receptor from rat pancreas using [125I]-Bolton Hunter CCK-8 as radioligand				J Med Chem 41: 1042-9 (1998) Article DOI: 10.1021/jm970373j BindingDB Entry DOI: 10.7270/Q2TQ60N3
					More data for this Ligand-Target Pair
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50063627 (CHEMBL9354 | N-(3-ethylesterbenzoicacid)-2-[3,4-di...) Show SMILES CCOC(=O)c1cccc(NC(=O)NNc2nc3ccccc3c(=O)n2-c2cccc(OC)c2)c1 Show InChI InChI=1S/C25H23N5O5/c1-3-35-23(32)16-8-6-9-17(14-16)26-25(33)29-28-24-27-21-13-5-4-12-20(21)22(31)30(24)18-10-7-11-19(15-18)34-2/h4-15H,3H2,1-2H3,(H,27,28)(H2,26,29,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton Hunter CCK-8 as radioligand				J Med Chem 41: 1042-9 (1998) Article DOI: 10.1021/jm970373j BindingDB Entry DOI: 10.7270/Q2TQ60N3
					More data for this Ligand-Target Pair