BDBM50063655 CHEMBL9492::N-(3-benzonitrile)-2-[3,4-dihydro-[3-phenyl]-4-oxo-2-quinazolinyl]hydrazinecarboxamide

SMILES: O=C(NNc1nc2ccccc2c(=O)n1-c1ccccc1)Nc1cccc(c1)C#N

InChI Key: InChIKey=HFBMZGINBOQMIT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50063655   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gastrin/cholecystokinin type B receptor (MOUSE)	BDBM50063655 (CHEMBL9492 | N-(3-benzonitrile)-2-[3,4-dihydro-[3-...) Show SMILES O=C(NNc1nc2ccccc2c(=O)n1-c1ccccc1)Nc1cccc(c1)C#N Show InChI InChI=1S/C22H16N6O2/c23-14-15-7-6-8-16(13-15)24-22(30)27-26-21-25-19-12-5-4-11-18(19)20(29)28(21)17-9-2-1-3-10-17/h1-13H,(H,25,26)(H2,24,27,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	262	n/a	n/a	n/a	n/a	n/a	n/a
Parke-Davis Pharmaceutical Research Curated by ChEMBL					Assay Description Binding affinity towards Cholecystokinin type B receptor (CCK-B) receptor in mouse cerebral cortex using [125I]-Bolton Hunter CCK-8 as radioligand				J Med Chem 41: 1042-9 (1998) Article DOI: 10.1021/jm970373j BindingDB Entry DOI: 10.7270/Q2TQ60N3
					More data for this Ligand-Target Pair