BDBM50064184 (2Z,4E)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-penta-2,4-dienoic acid ((1S,5R)-8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide::CHEMBL288419

SMILES: CO\C(=C/C=C/c1cc2cc(Cl)c(Cl)cc2[nH]1)C(=O)NC1C[C@@H]2CC[C@H](C1)N2C

InChI Key: InChIKey=AFQWTODAHLZPFL-MYGQRMOZSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50064184   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vacuolar H(+)-transporting ATPase 116 kDa subunit, a1 isoform (Gallus gallus)	BDBM50064184 ((2Z,4E)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-p...) Show SMILES CO\C(=C/C=C/c1cc2cc(Cl)c(Cl)cc2[nH]1)C(=O)NC1C[C@@H]2CC[C@H](C1)N2C |THB:28:27:20.21.26:23.24| Show InChI InChI=1S/C22H25Cl2N3O2/c1-27-16-6-7-17(27)11-15(10-16)26-22(28)21(29-2)5-3-4-14-8-13-9-18(23)19(24)12-20(13)25-14/h3-5,8-9,12,15-17,25H,6-7,10-11H2,1-2H3,(H,26,28)/b4-3+,21-5-/t15?,16-,17+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Compound was tested for inhibititon of V-ATPase from Chicken osteoclasts(cOc)				J Med Chem 41: 1568-73 (1998) Article DOI: 10.1021/jm9800144 BindingDB Entry DOI: 10.7270/Q2CJ8CM6
					More data for this Ligand-Target Pair
Vacuolar ATP synthase subunit B, kidney isoform (Homo sapiens (Human))	BDBM50064184 ((2Z,4E)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-p...) Show SMILES CO\C(=C/C=C/c1cc2cc(Cl)c(Cl)cc2[nH]1)C(=O)NC1C[C@@H]2CC[C@H](C1)N2C |THB:28:27:20.21.26:23.24| Show InChI InChI=1S/C22H25Cl2N3O2/c1-27-16-6-7-17(27)11-15(10-16)26-22(28)21(29-2)5-3-4-14-8-13-9-18(23)19(24)12-20(13)25-14/h3-5,8-9,12,15-17,25H,6-7,10-11H2,1-2H3,(H,26,28)/b4-3+,21-5-/t15?,16-,17+	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Compound was tested for inhibititon of V-ATPase from human kidney cortex(hK)				J Med Chem 41: 1568-73 (1998) Article DOI: 10.1021/jm9800144 BindingDB Entry DOI: 10.7270/Q2CJ8CM6
					More data for this Ligand-Target Pair
Vacuolar H(+)-transporting ATPase 116 kDa subunit, a1 isoform (Gallus gallus)	BDBM50064184 ((2Z,4E)-5-(5,6-Dichloro-1H-indol-2-yl)-2-methoxy-p...) Show SMILES CO\C(=C/C=C/c1cc2cc(Cl)c(Cl)cc2[nH]1)C(=O)NC1C[C@@H]2CC[C@H](C1)N2C |THB:28:27:20.21.26:23.24| Show InChI InChI=1S/C22H25Cl2N3O2/c1-27-16-6-7-17(27)11-15(10-16)26-22(28)21(29-2)5-3-4-14-8-13-9-18(23)19(24)12-20(13)25-14/h3-5,8-9,12,15-17,25H,6-7,10-11H2,1-2H3,(H,26,28)/b4-3+,21-5-/t15?,16-,17+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham S.p.A. Curated by ChEMBL					Assay Description Compound was tested for inhibititon of V-ATPase from Chicken adrenal glands(cAG)				J Med Chem 41: 1568-73 (1998) Article DOI: 10.1021/jm9800144 BindingDB Entry DOI: 10.7270/Q2CJ8CM6
					More data for this Ligand-Target Pair